Loss and acquisition of duck hepatitis B virus integrations in lineages of LMH-D2 chicken hepatoma cells
نویسندگان
چکیده
منابع مشابه
Duck hepatitis B virus integrations in LMH chicken hepatoma cells: identification and characterization of new episomally derived integrations.
While the cytoplasmic phase of the hepadnavirus replication cycle is well understood, very little is known about the nuclear phase. In contrast to retroviruses, proviral integration is not required for hepadnavirus replication; however, some of the viral DNAs in the nucleus are diverted into an integration pathway. Under certain conditions these integrations function as carcinogenic agents. In ...
متن کاملConditional replication of duck hepatitis B virus in hepatoma cells.
To facilitate investigations of replication and host cell interactions in the hepadnavirus system, we have developed cell lines permitting the conditional replication of duck hepatitis B virus (DHBV). With the help of this system, we devised conditions for core particle isolation that preserve replicase activity, which was not found in previous preparations. Investigations of the stability of v...
متن کاملEntry of Duck Hepatitis B Virus
* Corresponding author. Mailing address: 19 Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der 20 Universität Hamburg, Martinistrasse 52, D-20251 Hamburg, Germany. Phone: 21 49-40-48051 231, Fax: 49-40-48051 117, E-mail: [email protected]. 22 AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserv...
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15 صفحه اولThe Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran
Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1996
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.70.3.2000-2007.1996